Should i rail molly

Conversely the Danes and Kiwis chose snorting, whilst the Spanish and Belgians opted for the dab, when they were not swallowing a pill or capsule. Route and purity aside the other major factor impacting on the effects people get from powders is how much they use — dose pretty much can trump any effect of route of use if you take enough.

There was a huge variation among users from every country in how they usually measured their dose when using powder see Figure 2 below. The most common approach was to crush MDMA crystal and make a guess. After spending 9 hours in a lab crushing various pills and powders and weighing them for the pictures we used in the drugs meter minutes I can vouch that with practice this method may be more accurate that at first it might seem.

But I had the benefit of mg scales and measured every dose so I has a good idea of how good my guesses were over the course of the day. I think without some baseline reference point — this approach could be quite risky. Full marks must go the nearly 1 in 4 who weighed their powders out — that is the gold standard if you are using good scales. The takeaway message? How you use your MDMA matters. It is the primary psychoactive product found in ecstasy tablets, but these substances are rarely pure MDMA.

Instead, the illicit manufacture of ecstasy pills commonly involves combining MDMA with other substances such as caffeine, cocaine, amphetamine , ketamine, or opioids.

Ecstasy is commonly used in party and club environments due to its euphoric AND energizing high. Ecstasy can often be found in pill form, which some users crush in a powder for snorting insufflation.

Snorting ecstasy can cause its effects to peak sooner for the user and increase the dangers associated with use. Molly can be ingested in different ways and how rapidly the drug reaches the brain depends on how it was taken. The faster a drug enters the brain, the faster the rewarding effects are produced, and the more likely the person is to engage in further abuse or develop an addiction. When taken orally, the effects of ecstasy can be experienced around minutes after dosing—snorting the drug will cause these effects to manifest more quickly and to be felt more intensely, increasing the dangers associated with use.

Molly MDMA is often snorted, and doing so can cause effects to come on faster and have a briefer, more intense peak as the drug reaches the brain quicker. The ecstasy high can be a pleasant experience for the user—from increased sensory perception and empathic feelings toward others to feeling happy and energized.

But this euphoric high can have a sinister side. Ecstasy side effects can range from mildly uncomfortable to borderline life-threatening, and they vary depending on whether MDMA was used in conjunction with other substances. In addition to the drug-specific effects, snorting ecstasy can induce other types of damage to the nasal passages and surrounding nasal tissues.

Damage from nasal insufflation of MDMA can cause the following:. Many users use ecstasy in a highly social environment for enjoyment, including hours of dancing, often accidentally neglecting their health needs such as eating and drinking.

An MDMA overdose may occur as a consequence of several exaggerated physical responses that, in turn, impair essential life functions—processes such as heart rate and body temperature can become dangerously elevated and have disastrous results. Combined with inadequate hydration and diet, these effects can even be life-threatening in extreme situations. The chemical structure and the effects of MDMA are similar to amphetamine a stimulant and to mescaline a hallucinogen.

Some of the other drugs include caffeine , ephedrine, amphetamine , dextromethorphan, ketamine , and LSD. Ecstasy sometimes contains highly toxic drugs, such as paramethoxyamphetamine PMA , which can be lethal even in low doses.

MDMA was patented in and has been used experimentally, most notably as a supplement to psychotherapy in the s. Ecstasy is made in illegal labs with chemicals and processes that vary from lab to lab. Ecstasy is usually sold as a tablet or capsule that is swallowed. It may also be sold in powder form, or the tablets may be crushed and then snorted. There are also rare reports of the drug being injected. Ecstasy tablets come in different shapes, sizes and colours, and are often stamped with a logo, such as a butterfly or clover, giving them a candy-like look.

Tablets that are sold as ecstasy may not contain MDMA. The increased use of ecstasy as a recreational drug began in the s in the United States. Young people at raves all-night dance parties were the group most commonly associated with ecstasy use. While still used by young people in clubs and at parties, ecstasy is now also used by a wider range of people in a variety of settings.

A survey of Ontario students in grades 7 to 12 reported a decline in past-year use of ecstasy from six per cent in to 3. In low to moderate doses, ecstasy can produce feelings of pleasure and well-being, increased sociability and closeness with others. Like all stimulant drugs, ecstasy can make users feel full of energy and confidence.

Even at low doses, ecstasy can also have strong negative effects. Higher doses are unlikely to enhance the desirable effects, and may intensify the negative effects. The brain has protective mechanisms that regulate drug intake to minimize costs and maximize benefits. For example, alcohol can make you feel brave and allow you to interact with others with greater ease. This can be a benefit.

But at the same time, alcohol activates bitter taste receptors and also makes you feel dizzy. You could override both of these defenses if you really wanted to, but both can also protect you from drinking too much. Two recent events in our human history challenge these protective mechanisms: the availability of purer drugs and the use of direct routes of drug administration, like injection.

These developments allow us to get drugs into our brains faster and in a more spiking pattern — both of which increase the risk of addiction. Knowing this, we could manipulate pharmacokinetic variables to change how fast drug levels in the brain rise and fall, and transform the effects of drugs.

Manipulating these variables could make some drugs become more addictive, but it could also make some drugs go from being addictive to actually being therapeutic. We are already using some of these principles to treat addiction. Methadone is used to treat heroin addiction. At the moment, researchers are studying the possibility of using oral amphetamine to treat cocaine addiction.

When amphetamine is taken orally, drug levels rise in a slow and stable way. Wherever these ideas lead us, the available evidence already suggests that if we as addiction researchers ignore pharmacokinetics, we do so at our peril.